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In the 3 months prior, she had had bilateral progressive painless vision loss that resulted in blindness. There was no brain, retina, or vitreous infiltration or extracranial evidence of non-Hodgkin lymphoma (NHL).Ī 62-year-old woman with a brain lesion was referred to our neurosurgery department from ophthalmology. 16 This report describes a case of isolated optic chiasm and optic tract lymphoma that was diagnosed postoperatively in an immunocompetent patient. 9, 15 The median survival is 10–18 months in immunocompetent patients and shorter in patients with acquired immunodeficiency syndrome. In addition, chemotherapy, radiotherapy, and treatment with corticosteroids often produce only partial remission, and tumors recur in more than 90% of patients. 11–14 Due to the location of the tumor, resection is generally ineffective. 1 Sporadic case reports on isolated ONI as the initial manifestation of PCNSL have been published, 9, 10 but isolated lymphoma of the chiasm and optic tract is extremely rare. 7, 8Įye lesions that normally affect the retina, vitreous, or optic disc are found in approximately 20% of patients with PCNSL. 5, 6 Diagnosis has been made by optic nerve biopsy, according to some case reports. In systemic lymphoma, optic nerve involvement (ONI) has been reported as a primary symptom 4 or with recurrence. 2, 3 The cause of this increase is unknown.

1 Primary central nervous system lymphoma (PCNSL) is a rare intracranial lesion with a prevalence that increased by 10 times between 19. Lymphoma affects every organ in the body and presents with a variety of symptoms.

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